« Previous
Next »
Molecular Oncology
Volume 1, Issue 1
, Pages 84-96
, June 2007
The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression
References
- . A rapid in vitro assay for quantitating the invasive potential of tumor cells. Cancer Research. 1987;47:3239–3245
- Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nature Genetics. 2000;25:25–29
- . Functional differentiation and alveolar morphogenesis of primary mammary cultures on reconstituted basement membrane. Development. 1989;105:223–235
- . Variant glycosylation: an underappreciated regulatory mechanism for beta1 integrins. Biochimica et Biophysica Acta. 2004;1663:52–60
- Oncogenic pathway signatures in human cancers as a guide to targeted therapies. Nature. 2006;439:353–357
- . Parenchymal cells from adult rat liver in nonproliferating monolayer culture. I. Functional studies. Journal of Cell Biology. 1973;59:722–734
- . Morphology and function of cells of human embryonic liver in monolayer culture. Journal of Cell Biology. 1971;50:222–231
- . The differentiated state of normal and malignant cells or how to define a “normal” cell in culture. International Review of Cytology. 1981;70:27–100
- . How does the extracellular matrix direct gene expression?. Journal of Theoretical Biology. 1982;99:31–68
- . Microenvironmental regulators of tissue structure and function also regulate tumor induction and progression: the role of extracellular matrix and its degrading enzymes. Cold Spring Harbor Symposia on Quantitative Biology. 2005;70:343–356
- . Putting tumours in context. Nature Reviews Cancer. 2001;1:46–54
- . Tissue architecture: the ultimate regulator of breast epithelial function. Current Opinion in Cell Biology. 2003;15:753–762
- . Tissue structure, nuclear organization, and gene expression in normal and malignant breast. Cancer Research. 1999;59:1757–1763s(Discussion 1763s-1764s)
- . Trisomy 7p and malignant transformation of human breast epithelial cells following epidermal growth factor withdrawal. Cancer Research. 1996;56:2039–2044
- . A new diploid nontumorigenic human breast epithelial cell line isolated and propagated in chemically defined medium. In Vitro Cellular and Developmental Biology. 1987;23:181–188
- Genomic and transcriptional aberrations linked to breast cancer pathophysiologies. Cancer Cell. 2006;10:529–541
- . The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini. Cell. 2002;111:29–40
- . Akt activation disrupts mammary acinar architecture and enhances proliferation in an mTOR-dependent manner. Journal of Cell Biology. 2003;163:315–326
- . Maintenance and induction of morphological differentiation in dissociated mammary epithelium on floating collagen membranes. In Vitro. 1977;13:316–328
- . MDA-468, a human breast cancer cell line with a high number of epidermal growth factor (EGF) receptors, has an amplified EGF receptor gene and is growth inhibited by EGF. Biochemical and Biophysical Research Communications. 1985;128:898–905
- . Gene expression signature in organized and growth-arrested mammary acini predicts good outcome in breast cancer. Cancer Research. 2006;66:7095–7102
- Characterization of paired tumor and non-tumor cell lines established from patients with breast cancer. International Journal of Cancer. 1998;78:766–774
- . Novel role for PDEF in epithelial cell migration and invasion. Cancer Research. 2005;65:11572–11580
- Mechanisms of inactivation of E-cadherin in breast cancer cell lines. Cancer Research. 1998;58:1972–1977
- . Distinct roles of Akt1 and Akt2 in regulating cell migration and epithelial-mesenchymal transition. Journal of Cell Biology. 2005;171:1023–1034
- . Summaries of Affymetrix GeneChip probe level data. Nucleic Acids Research. 2003;31:e15
- . Breast cancer-associated PIK3CA mutations are oncogenic in mammary epithelial cells. Cancer Research. 2005;65:10992–11000
- . ERBB2 amplification in breast cancer analyzed by fluorescence in situ hybridization. Proceedings of the National Academy of Sciences of the United States of America. 1992;89:5321–5325
- . Targeting TACE-dependent EGFR ligand shedding in breast cancer. Journal of Clinical Investigation. 2007;117:337–345
- . Matrigel: basement membrane matrix with biological activity. Seminars in Cancer Biology. 2005;15:378–386
- . Overexpression of the EGF receptor-related proto-oncogene erbB-2 in human mammary tumor cell lines by different molecular mechanisms. EMBO Journal. 1987;6:605–610
- . Relevance of breast cancer cell lines as models for breast tumours: an update. Breast Cancer Research and Treatment. 2004;83:249–289
- . 3D culture models of normal and malignant breast epithelial cells. Nature Methods. 2007;4:359–365
- . Tissue phenotype depends on reciprocal interactions between the extracellular matrix and the structural organization of the nucleus. Proceedings of the National Academy of Sciences of the United States of America. 1998;95:14711–14716
- . Influence of a reconstituted basement membrane and its components on casein gene expression and secretion in mouse mammary epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 1987;84:136–140
- . Polarity and proliferation are controlled by distinct signaling pathways downstream of PI3-kinase in breast epithelial tumor cells. Journal of Cell Biology. 2004;164:603–612
- Chromatin organization measured by AluI restriction enzyme changes with malignancy and is regulated by the extracellular matrix and the cytoskeleton. American Journal of Pathology. 2005;166:1187–1203
- . Gradual selection of a cellular clone presenting a mutation at codon 179 of the p53 gene during establishment of the immortalized human breast epithelial cell line HMT-3522. Experimental Cell Research. 1994;215:380–385
- . ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini. Nature Cell Biology. 2001;3:785–792
- A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell. 2006;10:515–527
- . Serine phosphorylation-regulated ubiquitination and degradation of beta-catenin. Journal of Biological Chemistry. 1997;272:24735–24738
- . Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon. Proceedings of the National Academy of Sciences of the United States of America. 2006;103:12405–12410
- . Beta1 integrin inhibitory antibody induces apoptosis of breast cancer cells, inhibits growth, and distinguishes malignant from normal phenotype in three dimensional cultures and in vivo. Cancer Research. 2006;66:1526–1535
- Distinctive gene expression patterns in human mammary epithelial cells and breast cancers. Proceedings of the National Academy of Sciences of the United States of America. 1999;96:9212–9217
- . Molecular portraits of human breast tumors. Nature. 2000;406:747–752
- . Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 1992;89:9064–9068
- Genomic signatures to guide the use of chemotherapeutics. Nature Medicine. 2006;12:1294–1300
- . Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis. Nature Cell Biology. 2003;5:733–740
- . Extracellular matrix-dependent tissue-specific gene expression in mammary epithelial cells requires both physical and biochemical signal transduction. Proceedings of the National Academy of Sciences of the United States of America. 1994;91:12378–12382
- . A hierarchy of ECM-mediated signalling regulates tissue-specific gene expression. Current Opinion in Cell Biology. 1995;7:736–747
- . Modeling tissue-specific signaling and organ function in three dimensions. Journal of Cell Science. 2003;116:2377–2388
- . A novel transcriptional enhancer is involved in the prolactin- and extracellular matrix-dependent regulation of beta-casein gene expression. Molecular Biology of the Cell. 1992;3:699–709
- . Control of mammary epithelial differentiation: basement membrane induces tissue-specific gene expression in the absence of cell–cell interaction and morphological polarity. Journal of Cell Biology. 1991;115:1383–1395
- . Expression of extracellular matrix components is regulated by substratum. Journal of Cell Biology. 1990;110:1405–1415
- . Laminin mediates tissue-specific gene expression in mammary epithelia. Journal of Cell Biology. 1995;129:591–603
- . Mutant E-cadherin breast cancer cells do not display constitutive Wnt signaling. Cancer Research. 2001;61:278–284
- . Phenotypic reversion or death of cancer cells by altering signaling pathways in three-dimensional contexts. Journal of the National Cancer Institute. 2002;94:1494–1503
- . Reciprocal interactions between beta1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: a different perspective in epithelial biology. Proceedings of the National Academy of Sciences of the United States of America. 1998;95:14821–14826
- . Beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium. Cancer Cell. 2002;2:205–216
- . Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies. Journal of Cell Biology. 1997;137:231–245
- . Autocrine CSF-1R activation promotes Src-dependent disruption of mammary epithelial architecture. Journal of Cell Biology. 2004;165:263–273
- Xu, R., Spencer, V.A., Bissell, M.J., 2007. Extracellular matrix-regulated gene expression requires cooperation of SWI/SNF and transcription factors. Journal of Biological Chemistry, in press.
- . Controlled activation of ErbB1/ErbB2 heterodimers promote invasion of three-dimensional organized epithelia in an ErbB1-dependent manner: implications for progression of ErbB2-overexpressing tumors. Cancer Research. 2006;66:5201–5208
PII: S1574-7891(07)00007-5
doi: 10.1016/j.molonc.2007.02.004
© 2007 Federation of European Biochemical Societies. Published by Elsevier Inc. All rights reserved.
« Previous
Next »
Molecular Oncology
Volume 1, Issue 1
, Pages 84-96
, June 2007

