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Molecular Oncology
Volume 2, Issue 1
, Pages 16-19
, June 2008
NESH protein expression switches to the adverse effect of imatinib mesylate
References
- . Abi-2, a novel SH3-containing protein interacts with the c-Abl tyrosine kinase and modulates c-Abl transforming activity. Genes Dev. 1995;9:2569–2583
- . JAK-STAT signaling activated by Abl oncogenes. Oncogene. 2000;19:2523–2531
- . Development of multiple myeloma in a patient with chronic myeloid leukemia after treatment with imatinib mesylate. Oncologist. 2005;10:457–458
- . NESH (Abi-3) is present in the Abi/WAVE complex but does not promote c-Abl-mediated phosphorylation. FEBS Lett. 2006;580:6464–6470
- . Forced expression of NESH suppresses motility and metastatic dissemination of malignant cells. Cancer Res. 2002;62:2215–2219
- . Phosphorylation of c-Abl by protein kinase Pak2 regulates differential binding of ABI2 and CRK. Biochemistry. 2008;47:1094–1104
- . Unexpected rapid progression of metastatic adenoid cystic carcinoma during treatment with imatinib mesylate. Head Neck. 2005;27:1022–1027
- . Isolation and characterization of a novel human gene (NESH) which encodes a putative signaling molecule similar to e3B1 protein. Biochim Biophys Acta. 2000;1493:237–241
- . Leukemia stem cells in a genetically defined murine model of blast-crisis CML. Blood. 2007;110:2578–2585
- . STI571 as a targeted therapy for CML. Cancer Invest. 2003;21:429–438
- . Imatinib mesylate (STI571) inhibits multiple myeloma cell proliferation and potentiates the effect of common antimyeloma agents. Br J Haematol. 2003;123:858–868
- . c-Abl is activated by growth factors and Src family kinases and has a role in the cellular response to PDGF. Genes Dev. 1999;13:2400–2411
- . Abl-interactor-1, a novel SH3 protein binding to the carboxy-terminal portion of the Abl protein, suppresses v-abl transforming activity. Genes Dev. 1995;9:2583–2597
- . Down-regulation of WAVE3, a metastasis promoter gene, inhibits invasion and metastasis of breast cancer cells. Am J Pathol. 2007;170:2112–2121
- . Activation of Abl tyrosine kinases promotes invasion of aggressive breast cancer cells. Cancer Res. 2006;66:5648–5655
PII: S1574-7891(08)00036-7
doi: 10.1016/j.molonc.2008.03.003
© 2008 Federation of European Biochemical Societies. Published by Elsevier Inc. All rights reserved.
« Previous
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Molecular Oncology
Volume 2, Issue 1
, Pages 16-19
, June 2008

