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Molecular Oncology
Volume 4, Issue 3
, Pages 192-208
, June 2010
Histological types of breast cancer: How special are they?
References
- . Expression of luminal and basal cytokeratins in human breast carcinoma. J. Pathol. 2004;203:661–671
- . High frequency of coexistence of columnar cell lesions, lobular neoplasia, and low grade ductal carcinoma in situ with invasive tubular carcinoma and invasive lobular carcinoma. Am. J. Surg. Pathol. 2007;31:417–426
- . Morphologic and molecular evolutionary pathways of low nuclear grade invasive breast cancers and their putative precursor lesions: further evidence to support the concept of low nuclear grade breast neoplasia family. Am. J. Surg. Pathol. 2008;32:513–523
- . Integrated profiling of basal and luminal breast cancers. Cancer Res. 2007;67:11565–11575
- . Prospective identification of tumorigenic breast cancer cells. Proc. Natl. Acad. Sci. U.S.A. 2003;100:3983–3988
- . Does massively parallel DNA resequencing signify the end of histopathology as we know it?. J. Pathol. 2010;220:307–315
- . A synthetic lethal therapeutic approach: poly(ADP) ribose polymerase inhibitors for the treatment of cancers deficient in DNA double-strand break repair. J. Clin. Oncol. 2008;26:3785–3790
- . KIT is highly expressed in adenoid cystic carcinoma of the breast, a basal-like carcinoma associated with a favorable outcome. Mod. Pathol. 2005;18:1623–1631
- . Problems in Breast Pathology. London: W.B. Saunders Company Ltd; 1979;
- . The world health organization histological typing of breast tumors – second edition. The World Organization. Am. J. Clin. Pathol. 1982;78:806–816
- . Will cancer stem cells provide new therapeutic targets?. Carcinogenesis. 2005;26:703–711
- . Gene expression profiling shows medullary breast cancer is a subgroup of basal breast cancers. Cancer Res. 2006;66:4636–4644
- . Lobular and ductal carcinomas of the breast have distinct genomic and expression profiles. Oncogene. 2008;27:5359–5372
- . Translocations in epithelial cancers. Biochim. Biophys. Acta. 2009;1796:201–215
- . Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study. JAMA. 2006;295:2492–2502
- . Microarray-based gene expression profiling as a clinical tool for breast cancer management: are we there yet?. Int. J. Surg. Pathol. 2009;17:285–302
- . Mapping of DNA amplifications at 15 chromosomal localizations in 1875 breast tumors: definition of phenotypic groups. Cancer Res. 1997;57:4360–4367
- . Relating genotype and phenotype in breast cancer: an analysis of the prognostic significance of amplification at eight different genes or loci and of p53 mutations. Cancer Res. 2000;60:1077–1083
- . Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis. Cancer Cell. 2006;10:437–449
- . An estrogen receptor-negative breast cancer subset characterized by a hormonally regulated transcriptional program and response to androgen. Oncogene. 2006;25:3994–4008
- . Breast cancer, stem/progenitor cells and the estrogen receptor. Trends Endocrinol. Metab. 2004;15:193–197
- . Multiple ways of silencing E-cadherin gene expression in lobular carcinoma of the breast. Int. J. Cancer. 2001;92:404–408
- . FGFR1 amplification in breast carcinomas: a chromogenic in situ hybridisation analysis. Breast Cancer Res. 2007;9:R23
- . Pathological prognostic factors in breast cancer. II. Histological type. Relationship with survival in a large study with long-term follow-up. Histopathology. 1992;20:479–489
- . Invasive breast carcinoma. In: Tavassoli FA, Devilee P editor. WHO Classification of Tumours Pathology and Genetics of Tumours of the Breast and Female Genital Organs. Lyon: Lyon Press; 2003;
- . Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up. Histopathology. 1991;19:403–410
- . Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature. 2005;434:917–921
- . Identification of molecular apocrine breast tumours by microarray analysis. Oncogene. 2005;24:4660–4671
- . Highly recurrent der(1;16)(q10;p10) and other 16q arm alterations in lobular breast cancer. Genes Chromosomes Cancer. 1998;23:300–306
- . Germline BRCA1 mutations and a basal epithelial phenotype in breast cancer. J. Natl. Cancer Inst. 2003;95:1482–1485
- . Molecular pathology of NUT midline carcinomas. J. Clin. Pathol. 2008;
- . Specific morphological features predictive for the basal phenotype in grade 3 invasive ductal carcinoma of breast. Histopathology. 2006;49:22–34
- . Molecular analysis reveals a genetic basis for the phenotypic diversity of metaplastic breast carcinomas. J. Pathol. 2010;220:561–573
- . Molecular analysis of metaplastic breast carcinoma: high EGFR copy number via aneusomy. Mol. Cancer Ther. 2008;7:944–951
- Gorski, J.J., James, C.R., Quinn, J.E., Stewart, G.E., Staunton, K.C., Buckley, N.E., McDyer, F.A., Kennedy, R.D., Wilson, R.H., Mullan, P.B., Harkin, D.P., 2009. BRCA1 transcriptionally regulates genes associated with the basal-like phenotype in breast cancer. Breast Cancer Res. Treat., epub ahead of print.
- . Histogenesis and differentiation: a re-evaluation of these concepts as criteria for the classification of tumors. Hum. Pathol. 1986;17:212–215
- . Estrogen receptor status in breast cancer is associated with remarkably distinct gene expression patterns. Cancer Res. 2001;61:5979–5984
- . Do ‘basal-like’ breast cancers really exist?. Nat. Rev. Cancer. 2009;9:128–134
- . Basal cytokeratins and their relationship to the cellular origin and functional classification of breast cancer. Breast Cancer Res. 2005;7:143–148
- . In situ and invasive lobular neoplasia of the breast. Histopathology. 2008;52:58–66
- . Genetic changes of Wnt pathway genes are common events in metaplastic carcinomas of the breast. Clin. Cancer Res. 2008;14:4038–4044
- . Biphasic metaplastic sarcomatoid carcinoma of the breast. Ann. Oncol. 2006;17:605–613
- . Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics. Cancer Res. 2009;69:4116–4124
- . Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors. Genome Biol. 2007;8:R76
- . Molecular basis for estrogen receptor alpha deficiency in BRCA1-linked breast cancer. J. Natl. Cancer Inst. 2007;99:1683–1694
- . The molecular portraits of breast tumors are conserved across microarray platforms. BMC Genomics. 2006;7:96
- . Metaplastic breast carcinoma. Rare form of mammary cancer. N.Y. State J. Med. 1973;73:1078–1082
- . Genetic reclassification of histologic grade delineates new clinical subtypes of breast cancer. Cancer Res. 2006;66:10292–10301
- . Typical medullary breast carcinomas have a basal/myoepithelial phenotype. J. Pathol. 2005;207:260–268
- . CD44 is overexpressed in basal-like breast cancers but is not a driver of 11p13 amplification. Breast Cancer Res. Treat. 2010;120:95–109
- . Differentiation of lobular versus ductal breast carcinomas by expression microarray analysis. Cancer Res. 2003;63:7167–7175
- . Genomic instability in breast cancer: Pathogenesis and clinical implications. Mol. Oncol. 2010;4(3):255–266
- . Secretory breast carcinomas with ETV6–NTRK3 fusion gene belong to the basal-like carcinoma spectrum. Mod. Pathol. 2009;22:291–298
- . Multifactorial analysis of differences between sporadic breast cancers and cancers involving BRCA1 and BRCA2 mutations. J. Natl. Cancer Inst. 1998;90:1138–1145
- . The pathology of familial breast cancer: predictive value of immunohistochemical markers estrogen receptor, progesterone receptor, HER-2, and p53 in patients with mutations in BRCA1 and BRCA2. J. Clin. Oncol. 2002;20:2310–2318
- . Prediction of BRCA1 status in patients with breast cancer using estrogen receptor and basal phenotype. Clin. Cancer Res. 2005;11:5175–5180
- . Genomic profile of a secretory breast cancer with an ETV6–NTRK3 duplication. J. Clin. Pathol. 2009;62:604–612
- . Metaplastic breast carcinomas: are they of myoepithelial differentiation?: immunohistochemical profile of the sarcomatoid subtype using novel myoepithelial markers. Am. J. Surg. Pathol. 2005;29:347–353
- . Metaplastic breast carcinomas are negative for Her-2 but frequently express EGFR (Her-1): potential relevance to adjuvant treatment with EGFR tyrosine kinase inhibitors?. J. Clin. Pathol. 2005;58:700–704
- . ETV6 gene rearrangements in invasive breast carcinoma. Genes Chromosomes Cancer. 2005;44:103–108
- . p53 overexpression and mutation in metaplastic carcinoma of the breast: genetic evidence for a monoclonal origin of both the carcinomatous and the heterogeneous sarcomatous components. J. Pathol. 2004;204:131–139
- . Molecular signatures of metaplastic carcinoma of the breast by large-scale transcriptional profiling: identification of genes potentially related to epithelial–mesenchymal transition. Oncogene. 2007;26:7859–7871
- . Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers. Nat. Med. 2009;15:907–913
- . Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancer. Proc. Natl. Acad. Sci. U.S.A. 2007;104:12111–12116
- . Phenotypic evaluation of the basal-like subtype of invasive breast carcinoma. Mod. Pathol. 2006;19:264–271
- . Uncommon breast tumors in perspective: incidence, treatment and survival in the Netherlands. Int. J. Cancer. 2007;121:127–135
- . A fluorescence in situ hybridization study of ETV6–NTRK3 fusion gene in secretory breast carcinoma. Genes Chromosomes Cancer. 2004;40:152–157
- . High frequency of TP53 mutation in BRCA1 and sporadic basal-like carcinomas but not in BRCA1 luminal breast tumors. Cancer Res. 2009;69:663–671
- . Genomic and immunophenotypical characterization of pure micropapillary carcinomas of the breast. J. Pathol. 2008;215:398–410
- . Mixed micropapillary-ductal carcinomas of the breast: a genomic and immunohistochemical analysis of morphologically distinct components. J. Pathol. 2009;218:301–315
- . Tumor heterogeneity: causes and consequences. Biochim. Biophys. Acta. 2009;
- . A mouse model of basal-like breast carcinoma with metaplastic elements. J. Pathol. 2007;211:389–398
- . Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors. EMBO Mol. Med. 2009;1:315–322
- . The impact of translocations and gene fusions on cancer causation. Nat. Rev. Cancer. 2007;7:233–245
- . Is ‘basal-like’ carcinoma of the breast a distinct clinicopathological entity? a critical review with cautionary notes. Pathobiology. 2008;75:119–131
- . Calibration and discriminatory accuracy of prognosis calculation for breast cancer with the online Adjuvant! program: a hospital-based retrospective cohort study. Lancet Oncol. 2009;10:1070–1076
- . Inherited Forms of Breast Cancer, including BRCA1. Abstracts from EMBO Molecular Medicine Conference Common Molecular Mechanisms of Mammary Gland Development and Breast Cancer Progression. Dublin: University College; 2006;p. 30-1
- . Carcinomas with micropapillary morphology: clinical significance and current concepts. Adv. Anat. Pathol. 2004;11:297–303
- . Tiling path genomic profiling of grade 3 invasive ductal breast cancers. Clin. Cancer Res. 2009;15:2711–2722
- . Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma. Clin. Cancer Res. 2004;10:5367–5374
- . Diagnostic Histopathology of the Breast. Edinburgh: Churchill Livingstone; 1987;
- . Supervised risk predictor of breast cancer based on intrinsic subtypes. J. Clin. Oncol. 2009;27:1160–1167
- . Nestin is expressed in basal-like and triple negative breast cancers. J. Clin. Pathol. 2008;61:1045–1050
- . Molecular subtypes in breast cancer evaluation and management: divide and conquer. Cancer Invest. 2008;26:1–10
- . Pathological prognostic factors in breast cancer. IV: Should you be a typer or a grader? A comparative study of two histological prognostic features in operable breast carcinoma. Histopathology. 1995;27:219–226
- . Molecular portraits of human breast tumours. Nature. 2000;406:747–752
- . Recurrent fusion of MYB and NFIB transcription factor genes in carcinomas of the breast and head and neck. Proc. Natl. Acad. Sci. U.S.A. 2009;106:18740–18744
- . Triple-negative breast cancer: present challenges and new perspectives. Mol. Oncol. 2010;4(3):209–229
- . Breast cancer: origins and evolution. J. Clin. Invest. 2007;117:3155–3163
- . Genomic signatures to guide the use of chemotherapeutics. Nat. Med. 2006;12:1294–1300
- . Mammary development meets cancer genomics. Nat. Med. 2009;15:842–844
- . Molecular classification of breast cancer: limitations and potential. Oncologist. 2006;11:868–877
- . Morphological and immunophenotypic analysis of breast carcinomas with basal and myoepithelial differentiation. J. Pathol. 2006;208:495–506
- . Basal-like breast cancer: a critical review. J. Clin. Oncol. 2008;26:2568–2581
- . Prognostic significance of Nottingham histologic grade in invasive breast carcinoma. J. Clin. Oncol. 2008;26:3153–3158
- . Histologic grading is an independent prognostic factor in invasive lobular carcinoma of the breast. Breast Cancer Res. Treat. 2008;111:121–127
- . Tubular carcinoma of the breast: further evidence to support its excellent prognosis. J. Clin. Oncol. 2010;28:99–104
- . Next-generation sequencing. Breast Cancer Res. 2009;11(Suppl. 3):S12
- . EGFR amplification and lack of activating mutations in metaplastic breast carcinomas. J. Pathol. 2006;209:445–453
- . Metaplastic breast carcinomas are basal-like tumours. Histopathology. 2006;49:10–21
- . FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas. Clin. Cancer Res. 2006;12:6652–6662
- . Is acinic cell carcinoma a variant of secretory carcinoma? A FISH study using ETV6‘split apart’ probes. Histopathology. 2008;52:840–846
- . Breast cancer special types: why bother?. J. Pathol. 2008;216:394–398
- . Triple negative tumours: a critical review. Histopathology. 2008;52:108–118
- . Expression of cytokeratins 17 and 5 identifies a group of breast carcinomas with poor clinical outcome. Am. J. Pathol. 2002;161:1991–1996
- . Rosen’s Breast Pathology. second ed.. Philadelphia: Lippincott Williams & Wilkins; 2001;
- . Breast cancer molecular subtypes respond differently to preoperative chemotherapy. Clin. Cancer Res. 2005;11:5678–5685
- . Epigenetic and genetic alterations of APC and CDH1 genes in lobular breast cancer: relationships with abnormal E-cadherin and catenin expression and microsatellite instability. Int. J. Cancer. 2003;106:208–215
- . Caveolin 1 is overexpressed and amplified in a subset of basal-like and metaplastic breast carcinomas: a morphologic, ultrastructural, immunohistochemical, and in situ hybridization analysis. Clin. Cancer Res. 2007;13:90–101
- . Distribution and significance of caveolin 2 expression in normal breast and invasive breast cancer: an immunofluorescence and immunohistochemical analysis. Breast Cancer Res. Treat. 2008;110:245–256
- . Histological Typing of Breast Tumours. Geneva: World Health Organisation; 1968;
- . Mutation of FOXL2 in granulosa-cell tumors of the ovary. N. Engl. J. Med. 2009;360:2719–2729
- . Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution. Nature. 2009;461:809–813
- . Efficacy of neoadjuvant Cisplatin in triple-negative breast cancer. J. Clin. Oncol. 2010;28:1145–1153
- . Molecular evolution of breast cancer. J. Pathol. 2005;205:248–254
- . Columnar cell lesions of the breast: the missing link in breast cancer progression? A morphological and molecular analysis. Am. J. Surg. Pathol. 2005;29:734–746
- . Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc. Natl. Acad. Sci. U.S.A. 2001;98:10869–10874
- . Repeated observation of breast tumor subtypes in independent gene expression data sets. Proc. Natl. Acad. Sci. U.S.A. 2003;100:8418–8423
- . Breast cancer classification and prognosis based on gene expression profiles from a population-based study. Proc. Natl. Acad. Sci. U.S.A. 2003;100:10393–10398
- . Gene expression profiling in breast cancer: understanding the molecular basis of histologic grade to improve prognosis. J. Natl. Cancer Inst. 2006;98:262–272
- . Gene-expression signatures in breast cancer. N. Engl. J. Med. 2009;360:790–800
- . Complex landscapes of somatic rearrangement in human breast cancer genomes. Nature. 2009;462:1005–1010
- . Detection and analysis of mammary gland stem cells. J. Pathol. 2009;217:229–241
- . Molecular heterogeneity of breast carcinomas and the cancer stem cell hypothesis. Nat. Rev. Cancer. 2007;7:791–799
- . Pathology of the Breast. second ed.. Stamford: Appleton & Lange; 1999;
- . Invasive micropapillary carcinoma of the breast is associated with chromosome 8 abnormalities detected by comparative genomic hybridization. Hum. Pathol. 2002;33:628–631
- . Expression of the ETV6–NTRK3 gene fusion as a primary event in human secretory breast carcinoma. Cancer Cell. 2002;2:367–376
- . Intratumor genomic heterogeneity in breast cancer with clonal divergence between primary carcinomas and lymph node metastases. Breast Cancer Res. Treat. 2007;102:143–155
- . der(16)t(1;16)/der(1;16) in breast cancer detected by fluorescence in situ hybridization is an indicator of better patient prognosis. Genes Chromosomes Cancer. 1999;24:72–77
- . BRCA1 dysfunction in sporadic basal-like breast cancer. Oncogene. 2007;26:2126–2132
- . FGFR1 amplification drives endocrine therapy resistance and is a therapeutic target in breast cancer. Cancer Res. 2010;70:2085–2094
- . Basal-like breast cancer and the BRCA1 phenotype. Oncogene. 2006;25:5846–5853
- . Modelling breast cancer: one size does not fit all. Nat. Rev. Cancer. 2007;7:659–672
- . Gene expression profiling predicts clinical outcome of breast cancer. Nature. 2002;415:530–536
- . A gene-expression signature as a predictor of survival in breast cancer. N. Engl. J. Med. 2002;347:1999–2009
- . Identification of typical medullary breast carcinoma as a genomic sub-group of basal-like carcinomas, a heterogeneous new molecular entity. Breast Cancer Res. 2007;9:R24
- . E-cadherin inactivation in lobular carcinoma in situ of the breast: an early event in tumorigenesis. Br. J. Cancer. 1997;76:1131–1133
- . Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer. Lancet. 2005;365:671–679
- . Refinement of breast cancer classification by molecular characterization of histological special types. J. Pathol. 2008;216:141–150
- . Metaplastic breast carcinomas are basal-like breast cancers: a genomic profiling analysis. Breast Cancer Res. Treat. 2009;117:273–280
- . Mucinous and neuroendocrine breast carcinomas are transcriptionally distinct from invasive ductal carcinomas of no special type. Mod. Pathol. 2009;22:1401–1414
- . Breast cancer molecular profiling: a retrospective analysis of molecular subtype assignment using single sample predictors. Lancet Oncol. 2010;11:339–349
- . The molecular underpinning of lobular histological growth pattern: a genome-wide transcriptomic analysis of invasive lobular carcinomas and grade- and molecular subtype-matched invasive ductal carcinomas of no special type. J. Pathol. 2010;220:45–57
- . The contribution of gene expression profiling to breast cancer classification, prognostication and prediction: a retrospective of the last decade. J. Pathol. 2010;220:263–280
- . Histological and molecular types of breast cancer: is there a unifying taxonomy?. Nat. Rev. Clin. Oncol. 2009;6:718–730
- . An atlas of subgross pathology of the human breast with special reference to possible precancerous lesions. J. Natl. Cancer Inst. 1975;55:231–273
- . On the origin and progression of ductal carcinoma in the human breast. J. Natl. Cancer Inst. 1973;50:1111–1118
- . Genome-wide transcriptomic profiling of microdissected human breast tissue reveals differential expression of KIT (c-Kit, CD117) and oestrogen receptor-alpha (ERalpha) in response to therapeutic radiation. J. Pathol. 2009;219:131–140
- . Meta-analysis of gene expression profiles in breast cancer: toward a unified understanding of breast cancer subtyping and prognosis signatures. Breast Cancer Res. 2008;10:R65
- . Breast carcinoma – rare types: review of the literature. Ann. Oncol. 2009;20:1763–1770
- . Transdifferentiation of neoplastic cells. Med. Hypotheses. 2001;57:655–666
- . Different gene expression patterns in invasive lobular and ductal carcinomas of the breast. Mol. Biol. Cell. 2004;15:2523–2536
PII: S1574-7891(10)00026-8
doi: 10.1016/j.molonc.2010.04.004
© 2010 Federation of European Biochemical Societies. Published by Elsevier Inc. All rights reserved.
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Molecular Oncology
Volume 4, Issue 3
, Pages 192-208
, June 2010

