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Article Title |
Author(s) |
Type (Status) |
Available Online |
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Heterogeneity among RIP-Tag2 insulinomas allows vascular endothelial growth factor-A independent tumor expansion as revealed by studies in Shb mutant mice: Implications for tumor angiogenesis
DOI: 10.1016/j.molonc.2012.01.006
Abstract: The Shb adapter protein is a signaling intermediate that operates downstream of vascular endothelial growth factor receptor-2 (VEGFR-2) in endothelial cells. The Shb knockout mouse displays ...
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Björn Åkerblom,
Guangxiang Zang,
Zhen W. Zhuang,
Gabriela Calounova,
Michael Simons,
Michael Welsh
et al.
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Full-length article
(In Press Uncorrected Proof)
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06 February 2012 |
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Inhibition of NEDD8-conjugation pathway by novel molecules: Potential approaches to anticancer therapy
DOI: 10.1016/j.molonc.2012.01.003
Abstract: Cancer cells can survive through the upregulation of cell cycle and the escape from apoptosis induced by numerous cellular stresses. In the normal cells, these biological cascades depend on ...
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Tomoaki Tanaka,
Tatsuya Nakatani,
Tetsu Kamitani
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Review article
(In Press Uncorrected Proof)
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27 January 2012 |
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The toxin component of targeted anti-tumor toxins determines their efficacy increase by saponins
DOI: 10.1016/j.molonc.2012.01.004
Abstract: Tumor-targeting protein toxins are composed of a toxin enzyme coupled to a specific cell binding domain that targets cancer-associated antigens. The anti-tumor treatment by targeted toxins i...
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Alexander Weng,
Mayank Thakur,
Figen Beceren-Braun,
Diana Bachran,
Christopher Bachran,
Sebastian B. Riese,
Kristina Jenett-Siems,
Roger Gilabert-Oriol,
Matthias F. Melzig,
Hendrik Fuchs
et al.
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Full-length article
(In Press Uncorrected Proof)
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27 January 2012 |
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Germline pharmacogenomics in oncology: Decoding the patient for targeting therapy
DOI: 10.1016/j.molonc.2012.01.005
Abstract: Pharmacogenomics is the study of genetic factors determining drug response or toxicity. The use of pharmacogenomics is especially desirable in oncology because the therapeutic index of oncol...
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Peter H. O'Donnell,
Mark J. Ratain
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Review article
(In Press Uncorrected Proof)
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25 January 2012 |
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Structural and genic characterization of stable genomic regions in breast cancer: Relevance to chemotherapy
DOI: 10.1016/j.molonc.2012.01.001
Abstract: Background: Cancer genomes accumulate frequent and diverse chromosomal abnormalities as well as gene mutations but must maintain the ability to survive in vivo. We hypothesize that genetic s...
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Nicole I. Park,
Peter K. Rogan,
Heather E. Tarnowski,
Joan H.M. Knoll
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Full-length article
(In Press Uncorrected Proof)
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24 January 2012 |
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Cancer immunotherapy
DOI: 10.1016/j.molonc.2012.01.002
Abstract: The remarkable specificity of the immune system through antigen recognition has long attracted investigators to the possibility of immune-based therapy for cancer. Previous cancer immunother...
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Thomas F. Gajewski
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Review article
(In Press Corrected Proof)
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13 January 2012 |
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Adseverin: A novel cisplatin-resistant marker in the human bladder cancer cell line HT1376 identified by quantitative proteomic analysis
DOI: 10.1016/j.molonc.2011.12.002
Abstract: Cisplatin is currently the most effective antitumor agent available against bladder cancer. However, a majority of patients eventually relapse with cisplatin-resistant disease. Chemoresistan...
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Noriyoshi Miura,
Nobuaki Takemori,
Tadahiko Kikugawa,
Nozomu Tanji,
Shigeki Higashiyama,
Masayoshi Yokoyama
et al.
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Full-length article
(In Press Corrected Proof)
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12 January 2012 |
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The interaction of PKN3 with RhoC promotes malignant growth
DOI: 10.1016/j.molonc.2011.12.001
Abstract: PKN3 is an AGC-family protein kinase implicated in growth of metastatic prostate cancer cells with phosphoinositide 3-kinase pathway deregulation. The molecular mechanism, however, by which ...
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Keziban Unsal-Kacmaz,
Shoba Ragunathan,
Edward Rosfjord,
Stephen Dann,
Erik Upeslacis,
Mary Grillo,
Richard Hernandez,
Fiona Mack,
Anke Klippel
et al.
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Full-length article
(In Press Corrected Proof)
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03 January 2012 |
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Serous ovarian carcinoma patients with high alpha-folate receptor had reducing survival and cytotoxic chemo-response
DOI: 10.1016/j.molonc.2011.11.010
Abstract: The alpha-folate receptor (α-FR) is highly-expressed in various non-mucinous tumors of epithelial origin, including ovarian carcinoma. The aim of this study was to investigate the relationsh...
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Yu-Li Chen,
Ming-Cheng Chang,
Chia-Yen Huang,
Ying-Cheng Chiang,
Han-Wei Lin,
Chi-An Chen,
Chang-Yao Hsieh,
Wen-Fang Cheng
et al.
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Full-length article
(In Press Corrected Proof)
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29 December 2011 |